Depression is the most common mental disorder in the world. According to statistics, more than 350 million people of all ages suffer from depression, and more interestingly, two-thirds of them are women.
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Depression should be distinguished from the usual mood swings or negative emotional reactions, because this condition significantly reduces the quality of life of the patient, preventing him from working, studying, maintaining relationships with others and serving himself. In severe cases, depression leads to suicide, the victims of which annually become about 800 thousand people.
For those suffering from chronic depression, help might come from an unexpected source. According to new scientific studies, some compounds found in grapes naturally target biological mechanisms linked to anxiety and depression.
“The discovery of these new, natural grape-derived polyphenol compounds targeting cellular and molecular pathways associated with inflammation may provide an effective way to treat a subset of people with depression and anxiety, a condition that affects so many people,” said lead researcher Giulio Maria Pasinetti, Professor at Icahn School of Medicine at Mount Sinai in New York.
Researchers note that depression is associated with a variety of pathological processes, including inflammation of the peripheral immune system, a set of biological structures and processes in the lymph nodes and other tissues that protect against diseases and pathological conditions.
After analyzing the fruit of the grapes, the researchers found that they contain dihydrocaffeic (DHCA) acid and malvidin-3'-O-glucoside (Mal-gluc).
These compounds, according to researchers, affect the dynamics of synapses – the place of contact between the two neurons, which restore the ability of the brain to adapt to changing conditions and solve problems.
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They point out that the compounds found in grapes act differently from antidepressants, but the effect is about the same. At the same time, researchers explain that only grapes can not relieve a person from depression. But if you use grapes in combination with neurotransmitters, it works effectively, alleviating the symptoms and speeding up the recovery.
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